| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 14-09-25 0:30 | New England Revolution | Toronto FC | 1:1 |
| 14-09-25 0:30 | CF Montreal | St. Louis City SC | 0:2 |
| 14-09-25 0:30 | Cincinnati FC | Nashville SC | 2:1 |
| 14-09-25 0:30 | DC United | Orlando City | 1:1 |
| 14-09-25 0:30 | Charlotte FC | Inter Miami CF | 3:0 |
| 14-09-25 0:30 | Atlanta United FC | Columbus Crew | 4:5 |
| 14-09-25 1:40 | FC Dallas | Austin FC | 2:0 |
| 14-09-25 1:40 | Seattle Sounders | Los Angeles Galaxy | 2:2 |
| 14-09-25 1:40 | San Jose Earthquakes | Los Angeles FC | 2:4 |
| 14-09-25 1:40 | Chicago Fire | New York City FC | 1:3 |
| 14-09-25 2:30 | Real Salt Lake | Sporting Kansas City | 2:1 |
| 14-09-25 2:30 | Colorado Rapids | Houston Dynamo | 2:1 |
| 14-09-25 2:35 | Vancouver Whitecaps | Philadelphia Union | 7:0 |
| 14-09-25 3:30 | San Diego FC | Minnesota United FC | 1:3 |
| 14-09-25 3:30 | Portland Timbers | New York Red Bulls | 2:1 |
| 17-09-25 0:30 | Inter Miami CF | Seattle Sounders | -:- |